The Antimicrobial Activity of Sclerotia of Pleurotus tuberregium (Osu) on Some Clinical Isolates

This study was carried out to determine the medicinal potential of the sclerotia of Pleurotus tuberregium on some clinical isolates. The method employed for this test was the Kirby-Bauer disc-diffusion method. The ethanol extract showed some level of potency with zones of inhibition: Klebsiella sp (21 mm±0.2); Bacillus sp (15 mm±0.4); Staphylococcus aureus (13 mm±0.2); Candida albicans (7 mm± 0.1). Escherichia coli, Pseudomonas aeruginosa, Streptococcus sp were not susceptible to the ethanol extract. There was no observed level of susceptibility when hot and cold water extracts of sclerotia of Pleurotus tuberregium were used on the selected test organisms. Ethanol extract of sclerotia of P. tuberregium showed a good therapeutic outcome with its inhibitive effect on clinical isolates.