ABO-HP INTERACTION ANALYSIS

Two polymorphic systems, ABO blood groups and haptoglobin types, for 100 families with 281 living children from Patiala have been analysed to test the possible interaction between them. The interaction was seen in: (a) mother-child combinations and (b) different mating classes. Significant differences were seen in the ABO compatible and incompatible mother-child combinations. Hp1 gene frequency was high in the ABO incompatible combinations than the compatible. Likewise when the different matings (H X W) were divided into ABO compatible and incompatible, there was an excess of Hp1 gene frequency in the ABO incompatible matings.