HAEMOLITIC DISEASE OF THE NEWBORN, AN IMMUNE COMPLICATION OF PREGNANCY STILL IN FORCE

The Rhesus (Rh) blood type is one of the most complex and important blood groups in humans. Its assessment has remained a matter of primary importance in Neonatology, in order to prevent the hemolytic disease of the fetus and the newborn (HDFN). Anti-D antibodies cause the most severe form of HDFN, but there are also other Rh allo-antibodies capable of causing clinically severe HDFN. Hence, we report two cases of HDFN due to anti-Cw and anti-E antibodies, respectively, in which blood transfusion was needed because of important late-onset anemia.