Oral Sub Mucous Fibrosis: Comparison of Different Non Surgical Modalities

Background: Oral submucous fibrosis (OSMF) is a chronic, complex, irreversible, highly potent precancerous
condition characterized by juxta-epithelial inflammatory reaction and progressive fibrosis of
the sub mucosal tissues (lamina propria and deeper connective tissues). The condition is linked to
oral cancers and is associated with areca nut chewing, the main component of betel quid. Various
treatment modalities were compared the efficacy of intraoral administration of vitamin B combined
with lycopene with intralesional triamcinolone acetonide combined with hyaluronidase and oral vitamin
B complex with lycopene.
Objectives: To compare and evaluate the easy, safe and non invasive procedure for treatment of oral
submucous fibrosis.
Materials and Methods: Total of 30 patients with clinically diagnosed OSMF patients. Each group
consisted of ten patients with an age ranging from 30 -75years. A thorough case history along with a
detailed clinical examination was performed for all individuals. The interincisal mouth opening was
recorded at initial visit. Each group of patients received different modalities of theraphy for three
weeks and mouth opening was measured after three weeks modalities that were to be compared.
Group A Patients were advised use mixture of Turmeric and Jaggery Application twice a day all over
the oral mucosa. Group B patients were advised to use Topical Kenacort Application twice a day and
Group C patients were advised to do Physiotherapy exercise twice daily. The patients were recalled
after a period of three weeks and their inter-incisal mouth opening was recorded. The statistical
calculation was performed using SPSS version 19.
Results: 30-45 years - It was found that kenacort application suited the best treatment modality for
this age group as it showed a very good prognosis in the inter incisal mouth opening. 46-75 years - It
was found that jaggery and turmeric application suited the best treatment modality for this age group
as it showed a very good prognosis in the interincisal mouth opening.
Conclusion: In our study group jaggery and turmeric application found to be most easy effective and
safe modality of treatment for OSMF patients.