An Assessment of Heptoprotective Activity of Citrullus Lanatus in CCL4-Induced Hepatotoxicity in Rats l with Safety Profile Analysis

Humans have been discovering and incorporating medicinal plants, also known as medicinal herbs, into conventional medical processes since the beginning of time. The researchers investigated the effect of Citrullus lanatus extract on lipid profiles in rats. Throughout the treatment period, rats were given CCl4 and treatment species once a day. Both medium and high doses of the plant extract showed statistically significant (p < 0.05) changes in Serum Glutamic Pyruvic Transaminase (SGPT) and serum glutamic-oxaloacetic transaminase (SGOT) compared to the positive control group. Creatinine levels showed a statistically significant reduction (p < 0.05) at low, medium, and high doses. However, at high doses, urea demonstrated a statistically significant effect (p < 0.05).